The Dow Jones Industrial Average is falling Wednesday afternoon with shares of Salesforce Inc. and Microsoft facing the biggest drops for the blue-chip average. Shares of Salesforce Inc. CRM, -4.44% and Microsoft MSFT, -3.66% have contributed to the blue-chip gauge’s intraday decline, as the Dow DJIA, -0.42% was most recently trading 81 points (0.2%) lower. Salesforce Inc.’s shares have fallen $8.56 (4.1%) while those of Microsoft are off $9.78, or 3.2%, combining for an approximately 121-point drag on the Dow. Nike NKE, -2.98%, Dow Inc. DOW, -2.87%, and Visa V, -3.13% are also contributing significantly to the decline. A $1 move in any one of the 30 components of the index equates to a 6.59-point swing.